Cannabigerol, also known as CBG, is a molecule belonging to the cannabinoid family. According to consumer reviews, CBG is known for its potentially more potent effects than CBD. It is even believed to have powerful analgesic and anti-inflammatory effects.
When purchasing CBG products, you should choose your brand carefully, as there are many different types of products available, some of which are high-quality and others of average quality.
What is CBG?
CBG is a non-psychoactive substance naturally produced by the cannabis plant. It may offer numerous therapeutic benefits. It is the source of several other very important cannabinoids, such as THC and CBD, which is why it is present in such small amounts in the cannabis plant.
The Origins of CBG
Cannabigerol was discovered in cannabis by Gauni and Mechoulam in 1964 and is considered the missing link in the biosynthesis of THC.
CBG is produced from cannabigerolic acid (CBGa), the precursor to all cannabinoids found in the cannabis plant. In other words, CBD, CBC, CBN, and so on all come from CBG.
The Production of CBG
Cannabigerol is present throughout the growth process, particularly in young buds. Hemp must therefore be harvested as early as possible—even in the early stages of growth—to obtain the valuable CBG molecules. Full-spectrum or broad-spectrum extraction is then carried out using the supercritical CO₂ method.
Once mature, the CBG concentration is lower because it has been converted into CBD, CBN, etc. CBG is what we call a minor cannabinoid due to its rarity.
CBD crystals can also be obtained through other extraction methods, including CBG isolate.
Bioavailability of CBG in the Human Body
Understanding bioavailability is crucial if we want to maximize the potential of phytocannabinoids such as CBG. It is defined by the extent and rate at which a substance is absorbed into the bloodstream.
For example, during a blood transfusion, bioavailability is 100 percent because all the substances have been introduced into the bloodstream.
When a substance (such as a drug) is administered by other routes (inhalation, ingestion, topical application), its bioavailability is reduced because the substance is not completely absorbed.
Cannabinoids and CBG undergo a first-pass effect: once ingested, THC is converted into 11-hydroxy-THC, which produces a more intense sensation. The bioavailability of CBD and THC varies considerably depending on whether they are smoked, eaten, or drunk.
In general, studies show that full-spectrum products (such as CBG oil) are more effective when taken sublingually.
Full-spectrum CBG and the entourage effect
When combined with other phytocannabinoids and terpenes, the so-called “entourage effect” occurs. For example, CBG can counteract the psychoactive effects of THC and is classified as a CB1 receptor antagonist.
If you want to benefit from the potential entourage effects, we recommend that you always purchase full-spectrum products (or broad-spectrum products, which are similar but contain 0% THC). You should therefore avoid products made with CBG isolate, which are certainly less expensive but less effective, unless otherwise advised by a healthcare professional.
In fact, cannabinoids are much more effective when they interact with other cannabinoids, terpenes, flavonoids, vitamins, and other compounds found in the cannabis plant.
CBG and the Endocannabinoid System (ECS)
All vertebrates have an endocannabinoid system, which helps them maintain homeostasis. This biological system consists of various endocannabinoids, cannabinoid receptors, and enzymes distributed throughout the body. It is the largest neurotransmitter system.
The HPA axis keeps your mind and body in balance. It plays a very important role in regulating appetite, mood, pain, blood pressure, memory, hormones, and more. It also helps the body manage stress.
The SEC consists of three main parts:
- The CB1 and CB2 cannabinoid receptors,
- Endocannabinoids—or cannabinoids—that activate these receptors,
- And the metabolic cannabinoid enzymes that synthesize and break down phytocannabinoid molecules after they are used.
French Regulations on CBG Oil
In France, there are regulations governing the cultivation, importation, exportation, and sale of CBG, provided that the product is derived from a specific cannabis variety: Cannabis Sativa L. Furthermore, delta-9-tetrahydrocannabinol (THC), a psychoactive substance, is illegal, and its concentration in the product must not exceed 0.3%.
The relevant regulations also recommend that product labels provide consumers with accurate information, particularly regarding the ingredients of CBG oil, the company responsible for production, the product’s weight, and so on.
However, caution is advised, as consuming non-compliant products may subject buyers to penalties. In fact, the use of narcotics such as cannabis is punishable by up to one year in prison and a heavy fine (3,750 euros).
The Difference Between CBD and CBG
Although both CBG and CBD are derived from the hemp plant, their mechanisms of action in the body are slightly different. CBD alters the receptors’ ability to bind to cannabinoids, affecting the endocannabinoid system as a whole. CBG, on the other hand, targets specific receptors—namely the CB1 and CB2 receptors—which are associated with the brain and the central nervous system, respectively.
For example, CBG has been studied for its potential effects on specific conditions, such as inflammatory bowel disease, skin conditions like psoriasis, and even certain types of cancer. In addition, research has shown that CBG may possess antibiotic properties and could stimulate appetite. This could therefore be beneficial for people suffering from eating disorders such as anorexia.
A Few Tips for Choosing High-Quality CBG Oil
To help you choose a high-quality CBG oil, consider the following criteria:
The Origin and Cultivation Methods of Cannabis
The source of the hemp used in the CBG oil you choose is crucial. This is because cannabis is a bioaccumulative plant, meaning it absorbs substances present in the soil in which it is grown. Consequently, if the cannabis is grown in nutrient-rich soil, the final product will be high quality. On the other hand, if it was grown in soil containing toxins or heavy metals, these harmful substances will end up in your CBG oil. Choose products from organic farms and make sure you understand the farming practices used.
CBG Extraction Process
There are many ways to extract CBG, but not all methods produce oil of the same quality. The supercritical carbon dioxide extraction method is generally considered the best because it produces pure oil free of contamination. In addition, this method helps preserve the other cannabinoids present in the plant, which helps enhance the entourage effect. Avoid chemically extracted oils, as they may contain harmful solvent residues.
CBG concentration in the product
This factor determines the product’s effectiveness. Higher concentrations of CBG oil produce more pronounced effects, which can help relieve the symptoms of certain chronic or serious illnesses. However, if you’re looking to improve your overall health or manage everyday stress, a lower concentration of CBG oil should be sufficient. In any case, be sure to check the CBG content listed on the product label.
Conclusion
Overall, it’s important to choose your CBG oil wisely. So choose your CBG oil carefully and don’t just buy the first product you come across. Understand the source of the hemp used, the extraction process, and the CBG concentration in the product. You should also know the difference between full-spectrum, broad-spectrum, and CBG isolate. With this information, you can be sure to get a high-quality oil that delivers the benefits you’re looking for.
